DUOVIR 300mg/ 150mg

  • Generic Name – Lamivudine, Zidovudine, and Nevirapine
  • Strenght – 300mg / 150mg
  • Starting Pack – 60 tablet

The generic name for Lamivudine, Nevirapine and Zidovudine is Duovir-N. The drug comes under the reverse transcriptase inhibitor group of HIV medicines. It works by preventing the HIV virus from replicating within the host body.

Duovir-N is given to patients with Acquired Immunodeficiency Syndrome (AIDS).

Lamivudine, Nevirapine and Zidovudine does not prevent or cure HIV or AIDS. It only helps in controlling the replication of the virus within the body. One should not take Duovir-N if they have a known allergy to it or medicine that contains lamivudine, zidovudine or emtricitabine.

Do not take Duovir-N with other medicines that contain lamivudine or zidovudine. It may cause lactic acidosis in some patients. The symptoms of lactic acidosis include pain or weakness in muscles, numbness in limbs, breathing problems, nausea as well as vomiting.

Duovir-N can also cause severe damage to the liver. Call the doctor immediately if one develops severe pain in upper abdominal region radiating to the back, nausea and vomiting. It can also lead to clay colored stools, itching, loss of appetite and jaundice.

One should take precautions to avoid any secondary infections as Duovir-N reduces the number of white blood corpuses (WBC) in the blood. This increases the risk of infection.

The FDA places the drug under category C. The effects of the drug are not clear yet on a fetus. Thus, it is better to take the drug under a doctor’s guidance to avoid harming the fetus.

Take the drug according to the doctor’s instruction. Never alter the dose on your own. Make sure you take the drug as long as prescribed. In case you miss a dose, do not take the missed tablet if the time for the next dose is almost up. In case of overdose, call the doctor immediately and go to a hospital emergency room.

Some of the side effects of Duovir-N includes:

  • Nausea and/or vomiting
  • Headache
  • Dizziness
  • Drowsiness
  • Diarrhea
  • Lactic acidosis
  • Liver damage

Duovir can interact with other antiviral drugs such as ganciclovir, anticancer drugs such as doxorubicin, interferons, sulfa drugs. There are some drugs that may not interact with Lamivudine, Nevirapine and Zidovudine. Thus, make sure you inform your doctor all about the drugs, medications, herbal and vitamin supplements, health supplements, etc. before taking Duovir-N.